Very compact cores (n in the range 10^5-10^7cm-3) have been observed in absorption in the ISOCAM maps of the rho Ophiuchi main cloud, at 6.75 and 15 mic (Abergel et al. 1996). These cores allow to map the spatial variations of the infrared extinction properties of dust grains with the density and the local radiation field. Recent sub-mm observations on the balloon-borne PRONAOS-SPM have demonstrated that such cores are very cold, therefore the grain properties should drastically change inside these cores. We plane to analyse the variations of the silicate extinction features and also to look for the presence of a continum in the extinction curve from 5 to 16.5 mic.